Paramount Recruitment

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+44 (0)121 616 3460

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+1 833 455 3043

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Lead Computational Chemist – Cambridge

Lead Computational Chemist – Cambridge

Paramount is supporting a growing biotech startup in Cambridge which was established in 2016. The company was set up based on 15 years of high quality research from the University of Cambridge and they are progressing incredibly well. The team still work close to the University as a separate Drug Discovery arm, and in this role you will join a team with a real mix of academic and industry backgrounds working on small molecule projects.

The position is for an expert Computational Chemist (Senior-Principal level) to join as the first of its kind in the Medicinal Chemistry team. We are looking for a senior candidate with a broad set of informatics skills to lead the set up of their computational chemistry infrastructure, begin analysing and exploiting available data, work effectively with medicinal chemists to drive compound design and take on project leadership. They are also looking into applying more AI techniques, so this experience would be a huge bonus for us!

The company is very excited about this role and their portfolio is increasing! The culture there is a lot of fun, and this is a chance to work with a lot of freedom by driving your own activity alongside your experienced team. The successful candidate should have a strong desire to play a key role in discovering transformative treatments for debilitating diseases while working in an innovative and fast-paced environment.

Key Responsibilities

●Establish effective computational chemistry infrastructure according to scientific/business needs
●Collaborate effectively as a key member of Drug Discovery project teams
●Analyse and exploit all available data including kinetic, potency, ADME and physicochemical properties to design novel compounds to achieve multi-parameter optimisation
●Work effectively with Medicinal Chemists to drive highly effective compound design including applying ligand-based computational design and establishing predictive models for project data
●Exploit a broad range of informatics tools and databases, both internal and external, to utilize project data effectively
●Opportunity to take on project leadership of a Drug Discovery project
●Strong interpersonal and communication skills to work in a diverse, interdisciplinary and driven environment

●PhD in Organic Chemistry, Computational Chemistry or equivalent experience
●Greater than 5 years’ experience in a Pharmaceutical or Biotechnology context working in small molecule drug discovery projects
●Experience with Chem-/Bio-informatics platforms such as Dotmatics or Biovia is a plus
●Strong general IT skills
●An analytical mindset with superb communication, problem-solving and team working skills

Please contact Jade at for more information on this role or to arrange a call to discuss further. We look forward to hearing from you!

Keywords: Computational Chemistry, Cheminformatics, Small Molecule, Drug Discovery, Medicinal Chemistry, Biotechnology, Cambridge, London, Oxford

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Job Reference: JPLCC2608_1598437207

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Salary Currency: GBP

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Recruitment Consultant: Jade Page

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