1 month ago
Oxford Competitive Permanent
Job Reference: sd-srbioGT_1620748009
I am working with a Biotechnology company in Oxford who is recruiting for a Senior Bioinformatician to join their team. The company aims to deliver the next generation of immune-oncology medicines and they are currently developing small molecules to directly alter tumour cells.
The Senior Bioinformatician is responsible for analysis of diverse genomic, transcriptomic and immunopeptidomic preclinical and clinical data sets to provide unique biological insight for ongoing drug discovery and development programs. You will also contribute to company strategy decisions by being a key member of the core team.
*Responsible for compiling and analysing data sets to generate and test drug discovery / development hypotheses- including whole exome, RNA, gene expression arrays and immunopeptidomics.
*Responsible for combining appropriate company-specific data sets with public data sets
*Responsible for building bespoke analysis pipelines
*Responsible for the ongoing identification, mining and analysis of GWAS, PheWAS and other human genetics data resources
*Develop and maintain up-to-date computational analysis methods based on the latest literature and methods
*Develop machine learning algorithms for predicting omic changes
*Contribute to the setup and design of the IT infra-structure required for streamlined analysis and data storage
Experience and skills:
*PhD (or equivalent experience) in bioinformatics/computational biology and genomics
*Experience in drug discovery/development industry environment desired
*Excellent computational skills with experience in large-scale bioinformatics analysis of DNA, RNA and peptide sequence data
*Experience with scripting and/or programming for bioinformatics (e.g. proficiency in R and python programming)
*Experience of analysing publicly available GWAS and PheWAS datasets
*Awareness of machine learning based techniques
If you are interested in finding out more about this role then please get in touch with Sabrina Deo at email@example.com